Navigating The Intricacies Of ICD-10 For GIST: A Comprehensive Guide

What is ICD-10 for GIST?

ICD-10 stands for International Classification of Diseases, 10th Revision. It is a system used by healthcare providers to classify and code all diagnoses, symptoms, and procedures recorded in conjunction with hospital care in the United States. GIST, or Gastrointestinal Stromal Tumor, is a type of cancer that starts in the digestive tract, most commonly in the stomach or small intestine.

Code Information

Documenting Gastrointestinal Stromal Tumor (GIST) with ICD-
Documenting Gastrointestinal Stromal Tumor (GIST) with ICD-

The ICD-10 code for GIST is C49.9. This code is used to classify tumors of unspecified behavior in other sites within the digestive system. It is important for healthcare providers to accurately code for GIST in order to track and monitor the prevalence of this type of cancer.

Diagnostic Related Groups (MS-DRG)

ICD--CM Diagnosis Code C
ICD–CM Diagnosis Code C

MS-DRG, or Medicare Severity Diagnosis Related Group, is a system used to classify hospital cases into groupings that are expected to have similar hospital resource use. The MS-DRG code for GIST is 393, which falls under the category of other digestive system diagnoses.

Convert to ICD-9 Code

Documenting Gastrointestinal Stromal Tumor (GIST) with ICD-
Documenting Gastrointestinal Stromal Tumor (GIST) with ICD-

In order to convert the ICD-10 code for GIST (C49.9) to an ICD-9 code, you would use the code 171.9. This code is used for malignant neoplasm of the stomach, unspecified site.

Code History

The ICD-10 code for GIST has been in use since the implementation of the ICD-10 coding system in the United States on October 1, 2015. Prior to this, healthcare providers used the ICD-9 code 171.9 to classify GIST.

Approximate Synonyms

Some approximate synonyms for GIST include gastrointestinal stromal sarcoma, stromal tumor of the gastrointestinal tract, and GIST sarcoma. These terms are often used interchangeably in medical literature and coding.

Clinical Information

GIST is a rare type of cancer that originates in the interstitial cells of Cajal, which regulate the movement of food and liquid through the digestive system. These tumors can be benign or malignant, with the potential to spread to other parts of the body if not treated early and appropriately.


The exact cause of GIST is unknown, but research suggests that mutations in certain genes, such as KIT and PDGFRA, may play a role in the development of these tumors. Other risk factors for GIST include age, gender, and family history of the disease.


Symptoms of GIST can vary depending on the size and location of the tumor. Common symptoms include abdominal pain, bloating, nausea, vomiting, and blood in the stool. Some patients may also experience fatigue, weight loss, and loss of appetite.


Diagnosing GIST typically involves a combination of imaging tests, such as CT scans and MRI scans, as well as a biopsy to confirm the presence of the tumor. Healthcare providers may also perform blood tests to check for elevated levels of certain proteins associated with GIST.


Treatment for GIST often involves a combination of surgery, targeted therapy, and chemotherapy. Surgery is typically the primary treatment option for localized tumors, while targeted therapy drugs, such as imatinib and sunitinib, may be used to shrink or slow the growth of tumors that cannot be removed surgically.


In conclusion, ICD-10 coding for GIST plays a crucial role in accurately classifying and tracking cases of this rare type of cancer. Healthcare providers must be knowledgeable about the code for GIST in order to provide appropriate care and treatment for patients with this diagnosis.


Q: What is the ICD-10 code for GIST?
A: The ICD-10 code for GIST is C49.9.
Q: How is GIST diagnosed?
A: GIST is typically diagnosed through imaging tests and a biopsy to confirm the presence of the tumor.
Q: What are the treatment options for GIST?
A: Treatment for GIST may involve surgery, targeted therapy, and chemotherapy depending on the size and location of the tumor.
Q: Are there any risk factors for developing GIST?
A: Risk factors for GIST include age, gender, family history, and mutations in certain genes.
Q: How common is GIST?
A: GIST is considered a rare type of cancer, accounting for less than 1% of all gastrointestinal tumors.

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button