Understanding Metastatic Cholangiocarcinoma ICD-10 Codes And Diagnosis

Metastatic Cholangiocarcinoma ICD 10

Metastatic cholangiocarcinoma is a rare and aggressive form of bile duct cancer that has spread to other parts of the body. In ICD-10 coding, it is classified under C24.1. This type of cancer originates in the cells that line the bile ducts, which are small tubes that carry bile from the liver to the small intestine. When these cancerous cells metastasize, they can spread to nearby organs like the liver, gallbladder, pancreas, and lymph nodes, as well as to distant sites like the lungs and bones.

Code Information

The ICD-10 code for metastatic cholangiocarcinoma is C24.1. This code is used to classify and track cases of this specific type of cancer in medical records and databases. By using standardized codes like ICD-10, healthcare providers and researchers can easily identify and analyze trends in the incidence, prevalence, and outcomes of metastatic cholangiocarcinoma.

Diagnostic Related Groups (MS-DRG)

Frontiers  Emergence of Intrahepatic Cholangiocarcinoma: How High
Frontiers Emergence of Intrahepatic Cholangiocarcinoma: How High

Metastatic cholangiocarcinoma is typically classified under MS-DRG 378 – Major Gastrointestinal Disorders and Peritoneal Infections with MCC (Major Complications and Comorbidities). This DRG grouping helps healthcare providers determine the appropriate level of care and reimbursement for patients with metastatic cholangiocarcinoma based on the severity and complexity of their condition.

Convert to ICD-9 Code

In the previous ICD-9 coding system, metastatic cholangiocarcinoma was classified under code 156.1. While ICD-9 codes are no longer used for billing and reporting purposes, it is still valuable to be familiar with the older coding system to ensure continuity in medical records and historical data analysis.

Code History

ICD--CM Diagnosis Code C
ICD–CM Diagnosis Code C

The ICD-10 code for metastatic cholangiocarcinoma, C24.1, was introduced in 2016 as part of the tenth revision of the International Classification of Diseases. This update included new codes, terms, and guidelines to improve the accuracy and specificity of coding for various diseases and conditions, including metastatic cholangiocarcinoma.

Approximate Synonyms

Other terms and phrases that may be used interchangeably with metastatic cholangiocarcinoma include:

Cholangiocarcinoma: current knowledge and future perspectives
Cholangiocarcinoma: current knowledge and future perspectives

Secondary bile duct cancer
Advanced biliary tract carcinoma
Metastatic cholangiocarcinoma to the liver
Bile duct adenocarcinoma with distant metastasis

These synonyms help to describe the same underlying condition of cancerous cells spreading from the bile ducts to other parts of the body.

Clinical Information

Cholangiocarcinoma : the next horizon in mechanisms and
Cholangiocarcinoma : the next horizon in mechanisms and

Metastatic cholangiocarcinoma is often diagnosed at an advanced stage when the cancer has already spread beyond the primary site in the bile ducts. Common symptoms may include jaundice, abdominal pain, weight loss, fatigue, and nausea. Diagnostic tests like imaging studies (CT scan, MRI, PET scan), blood tests (liver function tests, tumor markers), and tissue biopsy are used to confirm the presence of metastatic cholangiocarcinoma and determine the extent of spread.


The exact cause of metastatic cholangiocarcinoma is unknown, but it is believed to be related to genetic mutations, chronic inflammation of the bile ducts (such as in cases of primary sclerosing cholangitis), bile duct stones, liver fluke infection, and exposure to certain toxins or chemicals. Risk factors for developing this type of cancer include age, gender (more common in males), smoking, obesity, and a family history of bile duct or liver cancer.


Signs and symptoms of metastatic cholangiocarcinoma may vary depending on the location and extent of metastasis, but common manifestations include:

Jaundice (yellowing of the skin and eyes)
Abdominal pain and swelling
Unexplained weight loss
Fatigue and weakness
Nausea and vomiting
Loss of appetite
Pale stools and dark urine

These symptoms can be non-specific and overlap with other conditions, so a thorough evaluation by a healthcare provider is necessary for an accurate diagnosis.


Diagnosing metastatic cholangiocarc

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